Shiff, Steven J.: search on Z-Library

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1

Linaclotide for Irritable Bowel Syndrome With Constipation: A 26-Week, Randomized, Double-blind, Placebo-Controlled Trial to Evaluate Efficacy and Safety

Chey, William D, Lembo, Anthony J, Lavins, Bernard J, Shiff, Steven J, Kurtz, Caroline B, Currie, Mark G, MacDougall, James E, Jia, Xinwei D, Shao, James Z, Fitch, Donald A, Baird, Mollie J, Schneier,

Journal:

American Journal of Gastroenterology

Year:

2012

Language:

english

File:

PDF, 332 KB

english, 2012

2

Altered gastric epithelial cell kinetics in Helicobacter pylori-associated intestinal metaplasia: Implications for gastric carcinogenesis

Ilias A. Scotiniotis, Theodore Rokkas, Emma E. Furth, Basil Rigas, Steven J. Shiff

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 359 KB

english, 2000

3

Two Randomized Trials of Linaclotide for Chronic Constipation

Lembo, Anthony J., Schneier, Harvey A., Shiff, Steven J., Kurtz, Caroline B., MacDougall, James E., Jia, Xinwei D., Shao, James Z., Lavins, Bernard J., Currie, Mark G., Fitch, Donald A., Jeglinski, Br

Journal:

Boston Medical and Surgical Journal

Year:

2011

Language:

english

File:

PDF, 616 KB

english, 2011

4

Safety and tolerability of linaclotide for the treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation: pooled Phase 3 analysis

Nee, Judy W., Johnston, Jeffrey M., Shea, Elizabeth P., Walls, Courtney E., Tripp, Kenneth, Shiff, Steven, Fox, Susan M., Bochenek, Wieslaw, Weissman, Darren, Currie, Mark G., Lembo, Anthony J.

Journal:

Expert Review of Gastroenterology and Hepatology

Year:

2019

Language:

english

File:

PDF, 1.20 MB

english, 2019

5

A 12-Week, Randomized, Controlled Trial With a 4-Week Randomized Withdrawal Period to Evaluate the Efficacy and Safety of Linaclotide in Irritable Bowel Syndrome With Constipation

Rao, Satish, Lembo, Anthony J, Shiff, Steven J, Lavins, Bernard J, Currie, Mark G, Jia, Xinwei D, Shi, Kelvin, MacDougall, James E, Shao, James Z, Eng, Paul, Fox, Susan M, Schneier, Harvey A, Kurtz, C

Journal:

American Journal of Gastroenterology

Year:

2012

Language:

english

File:

PDF, 375 KB

english, 2012

6

Su2033 Determining the Minimum Duration for Initial Treatment With Linaclotide in IBS-C Patients: Results From Pooled Phase 3 Trials

Chey, William D., Lavins, Bernard J., Shiff, Steven J., MacDougall, James E., Kurtz, Caroline B., Shi, Kelvin, Currie, Mark G., Johnston, Jeffrey M.

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 849 KB

english, 2013

7

Continuing Education and Meeting Calendar

Lacy, Brian E., Lembo, Anthony, Schey, Ron, Lavins, Bernard J., Eng, Paul F., Fox, Susan M., Jia, Xinwei D., Hao, Xinming, Currie, Mark G., Kurtz, Caroline B., Johnston, Jeffrey, Shiff, Steven J.

Journal:

Journal of the American Society of Echocardiography

Year:

2011

Language:

english

File:

PDF, 109 KB

english, 2011

8

T1817 Results From the Randomized Withdrawal Period of a Phase 3 Clinical Trial of Linaclotide in Chronic Constipation

Johnston, Jeffrey M., Schneier, Harvey, Lavins, Bernard J., Shiff, Steven J., MacDougall, James E., Kurtz, Caroline B., Currie, Mark G., Lembo, Anthony

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 106 KB

english, 2010

9

Nonsteroidal anti-inflammatory drugs and colorectal cancer: Evolving concepts of their chemopreventive actions

Steven J. Shiff, Basil Rigas

Journal:

Gastroenterology

Year:

1997

Language:

english

File:

PDF, 686 KB

english, 1997

10

Efficacy and Safety of Once Daily Linaclotide in Patients With Irritable Bowel Syndrome With Constipation: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial Followed by a 4-Week Randomized Withdrawal Period

Satish Rao, Anthony Lembo, Steven J. Shiff, Kelvin Shi, Jeffrey M. Johnston, Harvey Schneier

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 504 KB

english, 2011

11

Tu1423 Effects of Linaclotide on Straining Associated With Bowel Movements in Patients With Irritable Bowel Syndrome With Constipation (IBS-C): A Post Hoc Analysis of Pooled Data From Two Phase 3 Trials

Lembo, Anthony, Rao, Satish S., Shiff, Steven J., Lavins, Bernard J., MacDougall, James E., Shi, Kelvin, Schneier, Harvey, Currie, Mark G., Johnston, Jeffrey M.

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 250 KB

english, 2012

12

Mo2054 Assessing Abdominal and Bowel Symptoms Using Adequate Relief Based Thresholds: Results From 2 Phase 3 Trials of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation

Camilleri, Michael, Lembo, Anthony, Lavins, Bernard J., MacDougall, James E., Shiff, Steven J., Jia, Xinwei D., Currie, Mark G., Kurtz, Caroline B., Johnston, Jeffrey M.

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 700 KB

english, 2013

13

Tu1380 Assessing the Percent of Days Linaclotide Improved Abdominal Symptoms and Stool Frequency in Patients With IBS-C: A Pooled Analysis of Two Phase 3 Trials

Rao, Satish S., Chang, Lin, Hao, Xinming, Lavins, Bernard J., Shiff, Steven J., Cao, Xiaofan, Schneier, Harvey, Currie, Mark G., Johnston, Jeffrey M.

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 244 KB

english, 2012

14

Colon adenomatous polyps—do they grow inward?

Steven J Shiff, Basil Rigas

Journal:

Year:

1997

Language:

english

File:

PDF, 67 KB

english, 1997

15

848 Efficacy of Linaclotide in Improving Abdominal Symptoms Rated as Most Severe by Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

Satish S. Rao, Eamonn M. Quigley, Steven J. Shiff, Bernard J. Lavins, Caroline B. Kurtz, James E. MacDougall, Kelvin Shi, Harvey Schneier, Mark G. Currie, Jeffrey M. Johnston

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 139 KB

english, 2012

16

Staurosporine inhibits the proliferation, alters the cell cycle distribution and induces apoptosis in HT-29 human colon adenocarcinoma cells

Liang Qiao, Markos Koutsos, Li-Lan Tsai, Vassiliki Kozoni, Jeanette Guzman, Steven J. Shiff, Basil Rigas

Journal:

Year:

1996

Language:

english

File:

PDF, 2.18 MB

english, 1996

17

Response to Miner et al.

Currie, Mark G, Shiff, Steven J, Schneier, Harvey A, Johnston, Jeffrey M

Journal:

American Journal of Gastroenterology

Year:

2017

Language:

english

File:

PDF, 88 KB

english, 2017

18

Sulindac sulfide alters the expression of cyclin proteins in HT-29 colon adenocarcinoma cells

Liang Qiao, Steven J. Shiff, Basil Rigas

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 152 KB

english, 1998

19

Can Nonsteroidal Anti-Inflammatory Drugs Be Recommended to Prevent Colon Cancer in High Risk Elderly Patients?

Markos I. Koutsos,Steven J. Shiff,Dr Basil Rigas

Journal:

Year:

1995

Language:

english

File:

PDF, 902 KB

english, 1995

20

Nonsteroidal Antiinflammatory Drugs Inhibit the Proliferation of Colon Adenocarcinoma Cells: Effects on Cell Cycle and Apoptosis

Steven J. Shiff, Markos I. Koutsos, Liang Qiao, Basil Rigas

Journal:

Experimental Cell Research

Year:

1996

Language:

english

File:

PDF, 195 KB

english, 1996

21

Mo1856 Linaclotide Significantly Improved Abdominal Pain Compared With Placebo in Patients With Irritable Bowel Syndrome Regardless of Baseline Pain Severity in Two Phase 3 Trials

Schoenfeld, Philip S., Chey, William D., Lavins, Bernard J., Shiff, Steven J., Kurtz, Caroline B., MacDougall, James E., Jia, Xinwei D., Schneier, Harvey, Currie, Mark G., Johnston, Jeffrey M.

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 116 KB

english, 2012

22

Tu1069 Do Baseline Factors Contribute to Treatment Satisfaction in Patients With Chronic Constipation Treated With Linaclotide vs Placebo?

Schoenfeld, Philip S., Chang, Lin, Carson, Robyn, Shiff, Steven J., Lavins, Bernard J., MacDougall, James E., Jia, Xinwei D., Schneier, Harvey, Currie, Mark G., Johnston, Jeffrey M.

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 342 KB

english, 2012

23

10.1038/70909

Shiff, Steven J., Rigas, Basil

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 84 KB

english, 1999

24

236 Global Endpoints in IBS Clinical Trials: Results from a Phase 2B Study of Linaclotide

Jeffrey M. Johnston, James E. MacDougall, Bernard J. Lavins, Anthony J. Lembo, Harvey Schneier, Steven J. Shiff, Caroline B. Kurtz, Mark G. Currie

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 236 KB

english, 2009

25

Altered gastric epithelial cell kinetics inHelicobacter pylori-associated intestinal metaplasia: Implications for gastric carcinogenesis

Scotiniotis, Ilias A., Rokkas, Theodore, Furth, Emma E., Rigas, Basil, Shiff, Steven J.

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 346 KB

english, 2000

26

Sulindac sulfide induces several subpopulations of colon cancer cells, defined by PCNA/Ki-67 and DNA strand breaks

Liang Qiao, Steven J Shiff, Basil Rigas

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1997

Language:

english

File:

PDF, 288 KB

english, 1997

27

Sulindac sulfide inhibits the proliferation of colon cancer cells: diminished expression of the proliferation markers PCNA and Ki-67

Liang Qiao, Steven J. Shiff, Basil Rigas

Journal:

Year:

1997

Language:

english

File:

PDF, 624 KB

english, 1997

28

An observational study examining the impact of capecitabine on warfarin antithrombotic activity and bleeding complications

Ulcickas Yood, Marianne, Quesenberry, Charles P., Hensley Alford, Sharon, Tsai, Ai-Lin, Wells, Karen E., Yood, Steven M., Ackermann Shiff, Susan P.

Journal:

Current Medical Research and Opinion

Year:

2006

Language:

english

File:

PDF, 306 KB

english, 2006

29

Selection of topically applied non-steroidal anti-inflammatory drugs for oral cancer chemoprevention

Sandeep Sood, Steven J. Shiff, Chung S. Yang, Xiaoxin Chen

Journal:

Year:

2005

Language:

english

File:

PDF, 115 KB

english, 2005

30

Curcumin, a natural plant phenolic food additive, inhibits cell proliferation and induces cell cycle changes in colon adenocarcinoma cell lines by a prostaglandin-independent pathway

Rashid Hanif, Liang Qiao, Steven J. Shiff, Basil Rigas

Journal:

Journal of Laboratory and Clinical Medicine

Year:

1997

Language:

english

File:

PDF, 1.45 MB

english, 1997

31

Effect of aspirin on induction of apoptosis in HT-29 human colon adenocarcinoma cells

Liang Qiao, Rashid Hanif, Eleana Sphicas, Steven J. Shiff, Basil Rigas

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 1.57 MB

english, 1998

32

Effect of Linaclotide on Quality of Life in Adults With Chronic Constipation: Results From 2 Randomized, Double-Blind, Placebo-Controlled Phase III Trials

Robyn T. Carson, Stavros Tourkodimitris, James E. MacDougall, Barbara E. Lewis, Steven J. Shiff, Bernard J. Lavins, Caroline B. Kurtz, Anthony Lembo, Jeffrey M. Johnston

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 80 KB

english, 2010

33

M1345 Assessing Treatment Response in Chronic Constipation Clinical Trials: Concepts Elicited Through Qualitative Interviews With Patients

Fehnel, Sheri, Ervin, Claire, Shiff, Steven J., Johnston, Jeffrey M., Kurtz, Caroline B., Carson, Robyn T.

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 79 KB

english, 2010

34

T1273 Time to Onset of Linaclotide Effect On the Bowel Habits in Patients with Chronic Constipation: Results from a Phase 2B Study

Johnston, Jeffrey M., Lavins, Bernard J., MacDougall, James E., Lembo, Anthony J., Schneier, Harvey, Shiff, Steven J., Kurtz, Caroline B., Currie, Mark G.

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 96 KB

english, 2009

35

A review of the clinical efficacy of linaclotide in irritable bowel syndrome with constipation

Johnston, Jeffrey M., Shiff, Steven J., Quigley, Eamonn M.M.

Journal:

Current Medical Research and Opinion

Year:

2013

Language:

english

File:

PDF, 219 KB

english, 2013

36

286 Efficacy and Safety of Once Daily Linaclotide Administered Orally for 12-Weeks in Patients With Chronic Constipation: Results From 2 Randomized, Double-Blind, Placebo-Controlled Phase 3 Trials

Anthony Lembo, Harvey Schneier, Bernard J. Lavins, Steven J. Shiff, James E. MacDougall, Xinwei D. Jia, Caroline B. Kurtz, Mark G. Currie, Jeffrey M. Johnston

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 181 KB

english, 2010

37

The Effect of Linaclotide on Measures of Abdominal and Bowel Symptoms in Patients With Chronic Constipation and Abdominal Pain: Pooled Results From Two Phase 3 Trials

Anthony Lembo, Harvey Schneier, Bernard J. Lavins, Steven J. Shiff, James E. MacDougall, Xinwei D. Jia, Jeffrey M. Johnston

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 191 KB

english, 2011

38

Evaluating local vegetation cover as a risk factor for malaria transmission: a new analytical approach using ImageJ

Ricotta, Emily E, Frese, Steven A, Choobwe, Cornelius, Louis, Thomas A, Shiff, Clive J

Journal:

Malaria Journal

Year:

2014

Language:

english

File:

PDF, 1013 KB

english, 2014

39

Assessment of treatment response in chronic constipation clinical trials

Ervin, Claire, Fehnel, Sheri, Carson, Robyn, Johnston, Jeffrey, Shiff, Steven, Kurtz, Carolyn, Mangel, Allen, Baird, Mollie

Journal:

Clinical and Experimental Gastroenterology

Year:

2014

Language:

english

File:

PDF, 385 KB

english, 2014

40

Selected eicosanoids increase the proliferation rate of human colon carcinoma cell lines and mouse colonocytes in vivo

Liang Qiao, Vassiliki Kozoni, George J. Tsioulias, Markos I. Koutsos, Rashid Hanif, Steven J. Shiff, Basil Rigas

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1995

Language:

english

File:

PDF, 744 KB

english, 1995

41

157 Effect of Linaclotide On IBS-C Symptoms in the First Week of Treatment: Results from a Phase 2B Study

Anthony J. Lembo, Jeffrey M. Johnston, Bernard J. Lavins, James E. MacDougall, Harvey Schneier, Steven J. Shiff, Caroline B. Kurtz, Mark G. Currie

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 265 KB

english, 2009

42

Tu1401 Factors Contributing to Treatment Satisfaction in Patients With Irritable Bowel Syndrome With Constipation (IBS-C) Treated With Linaclotide vs Placebo

Lembo, Anthony, Carson, Robyn, Shiff, Steven J., Lavins, Bernard J., MacDougall, James E., Shi, Kelvin, Schneier, Harvey, Currie, Mark G., Johnston, Jeffrey M.

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 244 KB

english, 2012

43

Sulindac sulfide upregulates the Tcf4-b-catenin DNA binding complex in HT-29 colon carcinoma cells

Naik-Shrijay, Karuna, Rigas, Basil, Shiff, Steven J.

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 179 KB

english, 2000

44

Selective Induction of Colon Cancer Cell Apoptosis by 5-Fluorouracil in Humans

Rigas, Athanasios, Dervenis, Christos, Giannakou, Niki, Kozoni, Vassiliki, Shiff, Steven J., Rigas, Basil

Journal:

Cancer Investigation

Year:

2002

Language:

english

File:

PDF, 1.68 MB

english, 2002

45

Cyclooxygenase inhibitors: drugs for cancer prevention

Steven J Shiff, Punitha Shivaprasad, Diana L Santini

Journal:

Current Opinion in Pharmacology

Year:

2003

Language:

english

File:

PDF, 185 KB

english, 2003

46

Sa1098 Mediation Analysis Supports a Direct Effect of Linaclotide on Relief of Abdominal Pain Independent of Constipation Improvement

James E. MacDougall, David P. MacKinnon, Bernard J. Lavins, Anthony Lembo, Steven J. Shiff, Harvey Schneier, Xinming Hao, Mark G. Currie, Jeffrey M. Johnston

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 252 KB

english, 2012

47

418 Effect of Linaclotide On Quality of Life in Adults with Chronic Constipation: Results from a Phase 2B Study

Bernard J. Lavins, Jeffrey M. Johnston, James E. MacDougall, Anthony J. Lembo, Harvey Schneier, Steven J. Shiff, Robyn T. Carson, Caroline B. Kurtz, Mark G. Currie

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 153 KB

english, 2009

48

Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway

Rashid Hanif, Anastasios Pittas, Yan Feng, Markos I. Koutsos, Liang Qiao, Lisa Staiano-Coico, Steven I. Shiff, Basil Rigas

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.02 MB

english, 1996

49

Tu1070 The Effect of Linaclotide on IBS-QOL Sexual Subscale Scores in Patients With Irritable Bowel Syndrome With Constipation: Results From a Post Hoc Analysis of 2 Phase 3 Trials of Linaclotide

Currie, Mark G., Shiff, Steven J., Hao, Xinming, Carson, Robyn, Baird, Mollie J., Johnston, Jeffrey M.

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

50

Week 1 Changes in Bowel and Abdominal Symptoms Following Linaclotide Treatment: Results from Two Phase 3 Trials in Chronic Constipation Patients

Lembo, Anthony, Lavins, Bernard, Shiff, Steven, MacDougall, James, Kurtz, Caroline, OÊ¼Dea, Chris, Schneier, Harvey, Currie, Mark, Johnston, Jeffrey

Journal:

American Journal of Gastroenterology

Year:

2010

File:

PDF, 151 KB

2010

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